LL‑37 Peptide – 5mg Vial

High-purity research peptide for antimicrobial and immune response studies

LL‑37 is a human-derived antimicrobial peptide from the cathelicidin family, widely studied for its role in innate immunity, infection control, and tissue repair. It disrupts microbial membranes, regulates inflammation, and supports wound healing—making it a versatile candidate in host defense and regenerative research.

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🔬 Research Profile

• Antimicrobial action — LL‑37 targets bacteria, fungi, and enveloped viruses by disrupting their membranes and preventing biofilm formation.

• Immune modulation — Influences cytokine signaling and macrophage activity, helping balance inflammatory and healing responses.

• Tissue regeneration — Promotes epithelial repair, angiogenesis, and collagen synthesis, supporting wound closure and barrier integrity.

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🧪 Mechanism Highlights

• Expressed by neutrophils, epithelial cells, and macrophages in response to immune triggers.

• Activity is influenced by vitamin D and inflammatory signals.

• Found in skin, lungs, GI tract, and mucosal surfaces—key sites of pathogen exposure.

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⚙️ Applications in Research

• Infection models — LL‑37 is used to study resistance to Staphylococcus aureus, E. coli, and Candida albicans.

• Autoimmune and inflammatory pathways — Explored for its role in balancing immune overactivation.

• Cancer biology — Investigated for dual roles in tumor suppression and progression, depending on cell type.

• Wound care — Studied for its anti-biofilm effects and ability to accelerate healing in chronic wounds.

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📌 Product Details

• Use: For research use only. Not for human consumption.